490 - 4247 Homo sapiens - Deletions Deletion length: 3756 bp Does not remove any origin of replication Inside the minor arc	Breakpoint flanking sequences more information in Documentation - Flanking regions
	490 5fl vs 3del Homology length: 1 bp Deleted region 4247 TACTACTAATCTCATCAATA ├ 5'Breakpoint ┤ CAACCCCCGCCCATCCTACC (...) ACCCATTACAATCTCCAGCA ├ 3'Breakpoint ┤ TTCCCCCTCAAACCTAAGAA 5del vs 3del Homology length: 2 bp TACTACTAATCTCATCAATA ├ 5'Breakpoint ┤ CAACCCCCGCCCATCCTACC (...) ACCCATTACAATCTCCAGCA ├ 3'Breakpoint ┤ TTCCCCCTCAAACCTAAGAA

Two-dimensional scatterplot showing the location of the selected deletion (red diamond) versus the full dataset (grey dots). Each point represents an mtDNA rearrangement with the 5’ breakpoint on the x-axis and the 3’ breakpoint on the y-axis.	Circular mtDNA plot specifying the location of the deleted region (black bar).
Length distribution of the deleted region in the selected deletion (red bar) versus the full dataset (grey bars) .The cases were grouped 100-nt windows.

References

 [329] Vielhaber, Stefan, et al., Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion. Acta Neuropathologica. 2013. 125(2): p. 245-256.